Synthesis of various model compounds for the conjugated heterocyclic ring system of antibiotic roseophilin
β Scribed by Shogo Nakatani; Masayuki Kirihara; Kaoru Yamada; Shiro Terashima
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 271 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
A novel heterogeneous catalytic method to synthesize various heterocyclie compounds of biological interest, aminobenzisothiazole [.2a-h] and 1,3-thiazine derivatives [4, 6], using an environmentally attractive solid catalyst, zeolite, is described.
## Abstract The reactions of 5βnitroisatine were studied with nucleophiles like heterocyclic amines and alkaline hydroxide. With the use of alkaline hydroxide it was converted into 2βaminoβ5βnitrophenylglyoxylic acid **2**, with piperidine, morpholine and carbethoxypiperazine to its amides **4aβ4c*
## Abstract For Abstract see ChemInform Abstract in Full Text.