Synthesis of “V-Shaped” syn-Bidentate Ligands Based on Mesitylene-Derived [1.1.1.1]Metacyclophane Blocked in a 1,3-Alternate Conformation

✍ Scribed by Cédric Klein; Ernest Graf; Mir W. Hosseini; André De Cian; Nathalie Kyritsakas-Gruber

• Book ID: 102172674
• Publisher: John Wiley and Sons
• Year: 2003
• Tongue: English
• Weight: 110 KB
• Volume: 2003
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/ejoc.200390046

✦ Synopsis

Abstract

A series of five new syn‐bidentate ligands 14−18 based on the [1.1.1.1]metacyclophane backbone blocked in a 1,3‐alternate conformation was achieved. The common building block for the preparation of ligands bearing two interaction sites located in a syn fashion (CN, SMe, p‐pyridyl, p‐methoxyphenyl and p‐methylthiophenyl) is the dibromo derivative 12. All reported ligands were fully characterised by classical analytical methods and their 1,3‐alternate conformation demonstrated. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)