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Synthesis of unsaturated lactone moieties by asymmetric hetero Diels–Alder reactions with binaphthol-titanium complexes

✍ Scribed by Monika Quitschalle; Mathias Christmann; Ulhas Bhatt; Markus Kalesse


Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
65 KB
Volume
42
Category
Article
ISSN
0040-4039

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## Abstract Highly enantioselective Diels–Alder (DA) and inverse‐electron‐demand hetero‐Diels–Alder (HDA) reactions of β,γ‐unsaturated α‐ketoesters with cyclopentadiene catalyzed by chiral __N__,__N′__‐dioxide–Cu(OTf)~2~ (Tf=triflate) complexes have been developed. Quantitative conversion of β,γ‐un