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Synthesis of Unsaturated Amino Acids by [3,3]-Sigmatropic Rearrangement of Chelate-Bridged Glycine Ester Enolates

✍ Scribed by Dr. Uli Kazmaier


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
271 KB
Volume
33
Category
Article
ISSN
0044-8249

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Aldol reactions of a chelated glycine ester enolate with a azasugars by cyclization using the Mitsunobu reaction. An interesting epimerization was observed during the chiral aldehyde gives rise to the corresponding polyhydroxylated amino acid with excellent induced cyclization. The potential glycosi