Synthesis of Tyrosine-Derived Tetrahydroisoquinolines by Lewis Acid Catalyzed Cyclization of N-(Phenylsulfonyl)alkyloxazolidinones
✍ Scribed by Stefan Tussetschläger; Angelika Baro; Sabine Laschat; Wolfgang Frey
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 379 KB
- Volume
- 2007
- Category
- Article
- ISSN
- 1434-193X
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A convenient synthesis of (-)-N-styryl-N- [2-(1,7,7-trimethyl-yl)ethanol (6). Cyclization of the N-formylenamine 2 with the aid of 9-borabicyclo[3.3.1]non-9-yl triflate yielded a methano-bicyclo[2.2.1]hept-2-enyl)ethyl]formamide (2) was developed starting from natural (+)-camphor (3) via (-)-2-(born
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