Polarographic reduction of 1,5-diaza-4,8-dihydroxy-Len-butyl phenanthrene 2,6\_dicarboxylic acid (I) (IC174,917) closely resembles that of Qhydroxyquinaldinic acid (II). Reduction of both compounds is accompanied by three acid-base equilibria that of the ester (III) by two. Reduction of the carboxal
Synthesis of Two New Metal Ion Sequestering Agents: 1,4-Diaza-7-Thiacyclononane-N,N′-Diacetic Acid and of 1,5-Diaza-8-Thiacyclodecane-N,N′-Diacetic Acid
✍ Scribed by D. M. Wambeke; W. Lippens; G. G. Herman; A. M. Goeminne
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Weight
- 232 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0037-9646
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## Abstract The 1‐(5‐fluoro‐2‐pyridyl) or 1‐(3‐fluoro‐4‐pyridyl) group was introduced in the syntheses of new pyridonecarboxylic acid antibacterial agents. 1‐(5‐Fluoro‐2‐pyridyl)‐6‐fluoro‐1,4‐dihydro‐7‐(4‐methyl‐1‐piperazinyl)‐4‐oxoquinolone‐3‐carboxylic acid 7b (DW‐116) showed a moderate __in vitr
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