Synthesis of two analogues of a fragment of the complex polysaccharide C substance from Streptococcus pneumoniae type 1
β Scribed by J. P. G. Hermans; C. E. Dreef; P. Hoogerhout; G. A. van der Marel; J. H. van Boom
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 813 KB
- Volume
- 107
- Category
- Article
- ISSN
- 0165-0513
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π SIMILAR VOLUMES
Methyl 2-acetamido-4-amino-2,4,6-trideoxy-3-0-(~-D-galactopyranosyl-uronit acid)-cY-D-galactopyranoside has been synthesised. The parent disaccharide is a structural element of the capsular polysaccharide antigen of Streptococcus pneumoniae type 1.
The structure of the capsular polysaccharide from Streptococcus pneumoniae type 2 has been reinvestigated, specific degradations and n.m.r. spectroscopy being the main methods used. It is concluded that the polysaccharide is composed of hexasaccharide repeating-units having the following structure,