✦ LIBER ✦

Synthesis of tritium labelled thymic humoral factor γ2 (THF-γ2, thymoctonan)

✍ Scribed by E. Fontana; D. Giribone; A. Pignatti; M. Galantino; R. Forino; P. Dostert

Publisher: John Wiley and Sons
Year: 1996
Tongue: French
Weight: 248 KB
Volume: 38
Category: Article
ISSN: 0022-2135
DOI: 10.1002/(sici)1099-1344(199605)38:5<483::aid-jlcr853>3.0.co;2-o

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✦ Synopsis

The synthesis of the title compound labelled with tritium in the proline residue is reported. A five-step sequence starting f?om the commercially available fH]proline 1 afforded fHJTHF-y2 with a radiochemical purity 297Y0 and a high specific activity (>3.7 TBqlmmol). The overall radiochemical yield was about 15% from 1.