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Synthesis of tritium-labeled levetiracetam ((2S)-2-(2-oxopyrrolidin-1-yl)butanamide) with high specific activity

✍ Scribed by Simone Hildenbrand; Younis Baqi; Christa E. Müller

Publisher
John Wiley and Sons
Year
2011
Tongue
French
Weight
164 KB
Volume
55
Category
Article
ISSN
0022-2135

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✦ Synopsis

A method for the preparation of [³H]levetiracetam with a high specific activity of 98 Ci/mmol (3.6 TBq/mmol) is described. The radioligand proved to be highly useful for the labeling of specific levetiracetam binding sites in rat brain membrane preparations. Copyright © 2011 John Wiley & Sons, Ltd.

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