✦ LIBER ✦
Synthesis of tritiated Cyclosporin A and FK-506 by metal-catalyzed hydrogen isotope exchange
✍ Scribed by V. P. Shevchenko; I. Yu. Nagaev; N. F. Myasoedov; H. Andres; T. Moenius; A. Susan
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- French
- Weight
- 99 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0022-2135
- DOI
- 10.1002/jlcr.827
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Tritium‐labeled Cyclosporin A (I) and FK‐506 (II) have been prepared using a metal‐catalysed hydrogen isotope exchange procedure and high specific activity tritiated water. Specific activities of the labeled compounds were 0.15 and 0.59 TBq/mmol, respectively. Copyright © 2004 John Wiley & Sons, Ltd.