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Synthesis of Trifluoroethyl-Substituted Ketones from Aldehydes and Cyclohexanones

✍ Scribed by Bill Morandi; Prof. Dr. Erick M. Carreira


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
325 KB
Volume
50
Category
Article
ISSN
0044-8249

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Full exploitation of I70-NMR spectroscopy ['] in mechanistic organic chemistry requires efficient, simple methods for the synthesis of I70-labeled compounds. The classical method for labeling aldehydes and ketones with 1 7 0 or I8O is based on their reversible hydration['l. However, to obtain by thi