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Synthesis of tricyclic pyrido[2,3-b][1,4]-thiazines via nucleophilic substitution of activated precursors

✍ Scribed by Manuela Weber; Walter Jäger; Thomas Erker

Publisher
Journal of Heterocyclic Chemistry
Year
2003
Tongue
English
Weight
50 KB
Volume
40
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

Pyrido‐anellated compounds analogous to tricyclic 1,4‐benzothiazine derivatives were synthesized. Thus, under mild reaction conditiones substitution of thiolactim 3 with different N‐nucleophiles yielded the precursors for compounds, which were cyclized in a further step to the corresponding tricyclic derivatives.

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