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Synthesis of tri-, tetra-, and penta-deuterated forms of vitamin a

✍ Scribed by H. Robert Bergen; Harold C. Furr; James A. Olson

Book ID: 102375847
Publisher: John Wiley and Sons
Year: 1988
Tongue: French
Weight: 401 KB
Volume: 25
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580250103

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✦ Synopsis

analogs of retinoic acid ethyl ester and retinyl acetate, by a modified Wittig-Horner synthesis, is described. Deuterium was introduced by base-catalyzed e change into appropriate intermediates. topic integrity (>gas 2H4), is the preferred analog for biological studies of vitamin A metabolism.

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