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Synthesis of Thiochroman 1,1-Dioxide Derivatives on the Basis of 2,4,6-Trinitrotoluene.

✍ Scribed by V. A. Tartakovskii; S. A. Shevelev; M. D. Dutov; O. V. Serushkina; V. V. Kachala


Publisher
John Wiley and Sons
Year
2003
Weight
160 KB
Volume
34
Category
Article
ISSN
0931-7597

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## Abstract An improved and general synthesis of saccharin methylthio and methylsulfone derivatives from chlorosubstituted saccharins is presented. A large‐scale procedure for preparation of chloro‐substituted saccharins was developed. Treatment of the saccharin chlorides with sodium thiomethoxide