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Synthesis of thieno[2,3-b]azepin-4-ones as potential antineoplastic agents

โœ Scribed by Koebel, R. F.; Needham, L. L.; Blanton, C. De Witt


Book ID
111867745
Publisher
American Chemical Society
Year
1975
Tongue
English
Weight
450 KB
Volume
18
Category
Article
ISSN
0022-2623

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2-Deoxy-D-erythro-, ribo-, and arabino-pentofuranosylcytosines, which have a fluoromethyl group at the 4'-position, were synthesized. Introduction of fluorine was achieved by DAST treatment of 4-C-hydoxymethyI-D-ribofuranose, the key intermediate of 4'-C-methylnucleosides. Among these nucleosides, t