Synthesis of Thieno-Fused Heterocycles through Reiterative Iodocyclization
β Scribed by Aurelio, Luigi; Volpe, Rohan; Halim, Rosliana; Scammells, Peter J.; Flynn, Bernard L.
- Book ID
- 124147843
- Publisher
- John Wiley and Sons
- Year
- 2014
- Tongue
- English
- Weight
- 347 KB
- Volume
- 356
- Category
- Article
- ISSN
- 1615-4150
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π SIMILAR VOLUMES
The possibility to prepare fused tetrazole-and imidazole derivatives by iodocyclization in moderate to excellent yields is demonstrated. In some examples the cyclizations were not following Baldwin's rules entirely, i.e. exo-selectivity. Nucleophilic substitution of the formed iodides gave different
The reactivity of readily prepared heterocyclic enaminones with some doubly electrophilic reagents is described. Different classes of interesting fused heterocyclic systems are obtained from these enaminones in a single reaction. @