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Synthesis of thiazolines by the reaction of aryl ketonitriles with cysteamine via microwave irradiation

✍ Scribed by Sukanta Kamila; Edward R. Biehl


Publisher
Journal of Heterocyclic Chemistry
Year
2007
Tongue
English
Weight
203 KB
Volume
44
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

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Thiazolines were synthesized in a one‐pot reaction in excellent yield using a newly developed methodology. Ketonitriles were directly condensed with cysteamine (2‐amino‐thioalcohol) via microwave irradiation at 210Β°C for 10 minutes under solvent free conditions and without any solid support. All the compounds were characterized by ^1^H nmr, ^13^C nmr spectroscopy and elemental analyses.


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