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Synthesis of the Tetracyclic Bis(acetal) Lactone Portion of Saudin

✍ Scribed by Guillermo R. Labadie; Liliana E. Luna; Manuel Gonzalez-Sierra; Raquel M. Cravero


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
131 KB
Volume
2003
Category
Article
ISSN
1434-193X

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A Simple Synthesis of a Model of the Tet
✍ Guillermo R. Labadie; Liliana E. Luna; Raquel M. Cravero; Manuel González-Sierra 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 German ⚖ 101 KB

The partial structure 2 of the bisketal-type, tetracyclic saudin (1), an important natural product, was de novo synthesized. A key step was the Jones oxidation of the epoxide 3, which gave rise to epoxide-ring opening, followed by acetal hydrolysis, alcohol oxidation, and, finally, intramolecular ac

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