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Synthesis of the peptidic α-hydroxy amides phebestin, probestin, and bestatin from α-keto amide precursors

✍ Scribed by Harry H. Wasserman; Mingde Xia; Anders K. Petersen; Michael R. Jorgensen; Erin A. Curtis

Publisher: Elsevier Science
Year: 1999
Tongue: French
Weight: 214 KB
Volume: 40
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(99)01143-0

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✦ Synopsis

Aminopeptidase inhibitors, phebestin, probestin and bestatin have been prepared by stereospecific reduction of ot-keto amide precursors using zinc borohydride.

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