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Synthesis of the northern fragment of an epothilone D analogue from (−)-carvone

✍ Scribed by Ruslan F. Valeev; Radmir F. Bikzhanov; Niyaz Z. Yagafarov; Mansur S. Miftakhov


Book ID
116909566
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
283 KB
Volume
68
Category
Article
ISSN
0040-4020

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R)-Carvone is a suitable chiral template for the synthesis of differently protected (4S,6R,7R)-trihydroxy-l-octyne derivatives, the C27-C34 fragment of bryostatins. Also other potentially interesting chiral building blocks are described.