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Synthesis of the lactone precursor to hydroxyethylene dipeptide isostere from 3,4,6-tri-O-acetyl-D-glucal

✍ Scribed by Masao Shiozaki; Tadashi Hata; Youji Furukawa

Publisher: Elsevier Science
Year: 1989
Tongue: French
Weight: 147 KB
Volume: 30
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)80478-0

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✦ Synopsis

2S,4S,5S)-5-Amino-6-cyclohexyl-4-hydroxy-2-~sopropyl hexanoic acid lactone (5) was synthesized from x,4,6-tri-0-acetyl-D-glucal in an efficient manner.

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