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Synthesis of the Entire Carbon Framework (II) of the Kedarcidin Chromophore Aglycon.

โœ Scribed by Fumihiko Yoshimura; Martin J. Lear; Isao Ohashi; Yasuhito Koyama; Masahiro Hirama


Publisher
John Wiley and Sons
Year
2007
Weight
22 KB
Volume
38
Category
Article
ISSN
0931-7597

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Synthesis of the carbon framework of oli
โœ John H. Dodd; Steven M. Weinreb ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 169 KB

A convergent synthetic approach is outlined to the tricyclic compound I& which contains the full carbon skeleton of olivin. Olivin (A) is the aglycone of the olivomycin group of antitumor antibiotics. 2 These compounds, along with the structurally related chromomycins 3 and mithramycins, 4 are cur