Synthesis and stereochemical assignment
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K.C. Nicolaou; Kyo Han Ahn
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Article
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1989
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Elsevier Science
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French
⚖ 284 KB
Compound 8 representing fhe Ct-CtO fragment of nystafin At has been synthesized from nystafin Af by degradation and by total synthesis. Comparison of the two samples revealed the 3R, 5R, 7R stereochemistry for the three nystafin A I centers. Nystatin At (I)1 is a clinically used polyene macrolide