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Synthesis of the ABCD Ring System of Azaspiracid

✍ Scribed by K. C. Nicolaou; Wenyuan Qian; Federico Bernal; Noriaki Uesaka; Petri M. Pihko; Jürgen Hinrichs


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
144 KB
Volume
40
Category
Article
ISSN
0044-8249

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Scheme 1. Structure of azaspiracid (1) and retrosynthetic analysis leading to FGHI ring framework 3 via key intermediate 2. previously known agents of diarrhetic shellfish poisoning. [1] This seasonally occurring toxin displays an unusually complex molecular assembly ± it harbors a total of nine ri

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