Synthesis of the 9Z and 9Z, 11E isomers of leukotriene C4
โ Scribed by S.Richard Baker; William B. Jamieson; David J. Osborne; William J. Ross
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- French
- Weight
- 150 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
3Z,6E)-l-Bromododeca-3,6-diene, a common intermediate in the synthesis of labelled 12t linoleic acid and 14t arachidonic acid, was obtained from (E)-3-nonyl-l-ol, in four steps, via conventional functional manipulations. Cross-coupling of this bromododecadiene with the Grignard reagent of l-chloro-5
9-(ฮฒ-Pyridylmethylidene)-4-azafluorene. Synthesis of Z-and E-Isomers of Its Iodomethylate and Reduction of the Z-Isomer. -Reaction of azafluorene (I) with formylpyridine (II) affords an inseparable 1:1 mixture of E-and Z-isomers of pyridylmethylideneazafluorene (III). In contrast, the E-and Z-isom