The Donor-Acceptor-Acceptor Purine Analo
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Johannes J. Voegel; Michael M. Altorfer; Steven A. Benner
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Article
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1993
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John Wiley and Sons
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German
β 656 KB
A new synthesis is reported for 4-aminoimidazo[l,2-~]-1,3,5-triazin-2( IH)-one ( = 5-aza-7-deaza-isoguanosine; S), a purine analog that, when incorporated into an oligonucleotide chain, presents a H-bond donor-acceptor-acceptor pattern to a complementary pyrimidine analog. A protected ribose derivat