New tetracyclic derivatives (a;k, 5, 8) similar to protoberberinee, but containing a lactam structural element and other hetero atoms besides the bridgehead nitrogen in rings B and C, were prepared by cycloaddttion of 6,7-dimethoxy--2&1,3-benzothiazine (la) with q-substituted aromatic carboxylic aci
Synthesis of tetracyclic hydroxyquinones by cycloaddition reactions with dienols.
✍ Scribed by Alicia Amaro; M.Carmen Carreño; Francisco Fariña
- Book ID
- 104237888
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- French
- Weight
- 241 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
A new synthetic approach to quinazolines bearing a carboxy group is described. Reaction of 5-carbonyl substituted 1,3,6-trimethyluracils (I) with dimethyl acetylenedicarboxylate or electrondeficient olefines affords quinazoline derivatives (IU-VI) via pyrimidine(Z)-dienols (II) formed by base-cataly
## Abstract Herein we report a convergent enantioselective synthesis of a polyfunctionalized ABCD tetracycle by using an anionic cycloaddition reaction between a chiral bicyclic CD __Nazarov__ intermediate (see **6**), derived from the (−)‐__Weiland–Mischer__ ketone, and an achiral cyclohexenone (s