Synthesis of tetracyclic and pentacyclic phenothiazines via benzotriazole methodology
✍ Scribed by Alan R. Katritzky; Samia Agamy; Baozhen Yang; Guofang Qiu
- Book ID
- 102341307
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1999
- Tongue
- English
- Weight
- 300 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0022-152X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Treatment of 10‐(benzotriazol‐1‐yl)alkylphenothiazine with electron‐rich alkenes in the presence of zinc bromide gave tetracyclic phenothiazines 4 and 9 as well as pentacyclic phenothiazines 5, which have potential use in the pharmaceutical industry.
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## Abstract A novel method for the synthesis of 1,4‐ and 1,3,4‐substituted quinolinium salts and 1,2,4‐ and 1,2,3,4‐substituted‐1,2‐dibydroquinolines from __N__‐substituted‐__N__(benzotriazol‐1‐ylmethyl)aniline derivatives is reported.
## Abstract For Abstract see ChemInform Abstract in Full Text.