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Synthesis of taxane AB ring by intramolecular nitrile oxide cyclization reaction

✍ Scribed by Yoshimasa Hirai; Hiroto Nagaoka


Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
136 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis


The reaction of nitro olefin 9 with p-chlorophenyl isocyanate and triethyl amine produced tricyclic compound 10 having the taxane MB ring system with an aromatized C ring.


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