𝔖 Bobbio Scriptorium
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Synthesis of (±)-talaromycins A, B, C and E

✍ Scribed by Raymond Baker; Alastair L Boyes; Christopher J Swain


Book ID
104227089
Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
223 KB
Volume
30
Category
Article
ISSN
0040-4039

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Talaromycins C,D,E, and F
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An enantiospecific synthesis of (−)-tala
✍ Isidoro Izquierdo Cubero; Maria T. Plaza Lo´pez-Espinosa 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 833 KB

3R,4R,5S,6R,9RS)-9-Ethyl-3,4,5-trihydroxy-l,7-dioxaspiro[5.5]undecane (9) has been synthesised from 2,3:4,5-di-0-isopropylidene-/I-D-fructopyranose (3) and transformed into (-)-talaromycin A (1). (-)-Talaromycin B (2) was obtained by isomerisation of 1 in acid medium. \* Dedicated to Professor Lesli