𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of (−)-syringolides 1 and 2

✍ Scribed by Shigefumi Kuwahara; Masahiko Moriguchi; Kazuhiro Miyagawa; Masako Konno; Osamu Kodama


Book ID
103399550
Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
512 KB
Volume
51
Category
Article
ISSN
0040-4020

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


An improved synthesis of (−)-syringolide
✍ Pei Yu; Qi-Guang Wang; Thomas C.W. Mak; Henry N.C. Wong 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 345 KB

On treatment with 10% HF, butenolides 4a and 4b afforded enantiopure (-)-syringolides 1 (la) and 2 (lb) respectively in much higher yields. Unprecedentedly, the cyclic acetal 5a was also converted to la by reacting with an excess of p-TsOH. The structure of the ~ynthetic (-)-syringolide 1 (la) was s