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Synthesis of symmetrical diaryl ethers from arylboronic acids mediated by copper(II) acetate

✍ Scribed by A.D. Sagar; R.H. Tale; R.N. Adude

Book ID
104254341
Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
108 KB
Volume
44
Category
Article
ISSN
0040-4039

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Synthesis of diaryl ethers through the c
Synthesis of diaryl ethers through the copper-promoted arylation of phenols with arylboronic acids. An expedient synthesis of thyroxine
✍ David A Evans; Jeffrey L Katz; Theodore R West πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 287 KB

Diaryl ethers are readily synthesized in high yield at room temperature through the copper(II)-prorooted coupling of arylboronic acids and phenols. The reaction is tolerant of a wide range of substituents on both coupling partners. These reaction conditions permit the racemization-free arylation of