Synthesis of sugar-derived phostones by activation of γ-hydroxyphosphonic acids

✍ Scribed by Michaël Bosco; Philippe Bisseret; Jacques Eustache

• Book ID: 104253154
• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 170 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(03)00240-5

✦ Synopsis

Treatment of carbohydrate-derived g-hydroxyphosphonic acids under usual acetylation conditions affords the corresponding phostones in good yield. The method could be used for the preparation of free phostones as well as aand b-phosphonomethylarabinose.