Synthesis of Substituted Thiophenes by Palladium-Catalyzed Heterocyclodehydration of 1-Mercapto-3-yn-2-ols in Conventional and Nonconventional Solvents
β Scribed by Gabriele, Bartolo; Mancuso, Raffaella; Veltri, Lucia; Maltese, Vito; Salerno, Giuseppe
- Book ID
- 120052147
- Publisher
- American Chemical Society
- Year
- 2012
- Tongue
- English
- Weight
- 283 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0022-3263
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
A simple and economical synthesis of substituted furans and pyrroles, by ligand-free CuCl 2 -catalyzed heterocyclodehydration of readily available 3-yne-1,2-diols and N-Boc-or N-tosyl-1-amino-3-yn-2-ols, respectively, is presented. Reactions are carried out in MeOH at 80-100 Β°C for 1-24 h and afford