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Synthesis of substituted thiazoles and oxazoles from 2-amino-1-(p-nitrophenyl)ethanol

✍ Scribed by M. O. Lozinskii; T. N. Soroka; D. F. Yavorskii; S. S. Kirienko; V. Ya. Yakovleva; P. S. Pel'kis

Book ID
112326012
Publisher
Springer US
Year
1972
Tongue
English
Weight
178 KB
Volume
5
Category
Article
ISSN
0009-3122

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## Abstract The reactions of 4‐bromoacetyl‐3‐methoxy‐3‐methyl‐6,6‐diphenyl‐1,2‐dioxane with thioureas or thioamides gave 3‐methoxy‐3‐methyl‐6,6‐diphenyl‐4‐(4‐thiazolyl)‐1,2‐dioxanes in 63–90% yields. The similar reaction of 4‐bromoacetyl‐3‐methoxy‐3‐methyl‐6,6‐diphenyl‐1,2‐dioxane with acetamide ga