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Synthesis of substituted tetrahydro-1,3-oxazines

✍ Scribed by I. P. Boiko; Yu. E. Kazantsev; Yu. F. Malina; O. I. Zhuk; Yu. Yu. Samitov; B. V. Unkovskii


Book ID
112326333
Publisher
Springer US
Year
1973
Tongue
English
Weight
345 KB
Volume
9
Category
Article
ISSN
0009-3122

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Stereoselective synthesis of Ξ²-substitut
✍ Guillaume Burtin; Pierre-Jean Corringer; Peter B. Hitchcock; Douglas W. Young πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 258 KB

Oxazinones have been synthesised and used as chiral templates in the synthesis of I~substituted aspartic acids. Use of a Bredmvck's reagent/Grigaard/hydrogenation strategy gave c/soxazinones with complete stereoseleetivity, whereas an alkylation strategy, although trans-selective, gave mixtures of i