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SYNTHESIS OF SUBSTITUTED QUINOLYLAMINES. DERIVATIVES OF 4-AMINO-7-CHLOROQUINOLINE

✍ Scribed by BACHMAN, G. BRYANT; BENNETT, GEORGE E.; BARKER, ROBERT S.


Book ID
121392635
Publisher
American Chemical Society
Year
1950
Tongue
English
Weight
484 KB
Volume
15
Category
Article
ISSN
0022-3263

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Comparison of the biological effects in
✍ S. DechezleprΓͺtre; P. Lechat πŸ“‚ Article πŸ“… 1975 πŸ› Springer-Verlag 🌐 English βš– 304 KB

When given orally in elevated but nonlethal doses (150 to 450 mg/kg, on 2 consecutive days), glafenine induces in rats (body weight 100 g) a transient nephritis with an increase in blood urea, hypertrophy of adrenals, and some changes in the serum proteinogram. These effects do not appear to be due