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Synthesis of some tricyclic analogs of tetracycline

✍ Scribed by Howard J. Schaeffer; Girish B. Chheda


Publisher
John Wiley and Sons
Year
1964
Tongue
English
Weight
809 KB
Volume
53
Category
Article
ISSN
0022-3549

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The mono-, di-and spirocyclic silaalkanes 5, 6 and 9/10 are readily prepared from the di-and tetraallylsilanes 4 and 8 respectively by Cp2Zr induced ring forming reactions. The diallylsilole 16 reacts at 0Β°C and in presence of an excess of Cp2Zr to the tricyclic compound 19 whereas the silaspiro[4.4