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Synthesis of some radiolabeled 17α-ethynyl-19-nor steroids

✍ Scribed by J. A. Kepler; G. F. Taylor

Publisher
John Wiley and Sons
Year
1971
Tongue
French
Weight
229 KB
Volume
7
Category
Article
ISSN
0022-2135

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✦ Synopsis

During the course of study of the metabolism of some anti-fertility drugs it was necessary to prepare several 17cc-ethynyl-19-nor steroids. Although the use of some of the specifically labeled drugs reported here have been cited in the literature

The synthetic scheme employed for the preparation of these steroids is outlined in Chart I. Estradiol labeled either in the 6,7-positions with tritium

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