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Synthesis of some pyrazolopyrimidines as purine analogues

✍ Scribed by Sayed A. Ahmed; Ahmed M. Hussein; Walaa G. M. Hozayen; Ahmed H. H. El-Ghandour; Abdou O. Abdelhamid

Publisher
Journal of Heterocyclic Chemistry
Year
2007
Tongue
English
Weight
472 KB
Volume
44
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

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Pyrazolo[1,5‐a]pyrimidines were synthesized from the appropriate 3‐aminopyrazoles with the appropriate sodium (3‐oxocycloalkylidene)methenolate, β‐diketone, β‐keto esters or 1,2‐disubstituted acrylonitrile. Elemental analyses, spectral data, alternative synthesis route and X‐ray elucidated structures of the newly synthesized compounds.

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Synthesis of some new pyrazole and pyraz
Synthesis of some new pyrazole and pyrazolopyrimidine derivatives
✍ Said A. S. Ghozlan; Fathy M. Abdelrazek; Mona H. Mohamed; Khaled E. Azmy 📂 Article 📅 2010 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 204 KB

## Abstract magnified image A series of pyrazolo [3,4‐d] pyrimidine, pyrazolo [1,5‐a] pyrimidine, and pyrazolyl triazoles have been prepared __via__ reaction of ethyl 5‐amino‐3‐phenylpyrazole‐4‐carboxylate with isothiocyanic esters, α,β‐unsaturated nitriles, and some active methylene reagents. J. H