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Synthesis of some novel 2-substituted-5-[isopropylthiazole] clubbed 1,2,4-triazole and 1,3,4-oxadiazoles as potential antimicrobial and antitubercular agents

✍ Scribed by G.V. Suresh Kumar; Y. Rajendraprasad; B.P. Mallikarjuna; S.M. Chandrashekar; C. Kistayya


Book ID
108116395
Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
647 KB
Volume
45
Category
Article
ISSN
0223-5234

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## Abstract Several derivatives of substituted 1,2,4‐triazole bearing the pyrazole (or oxadiazole) ring were synthesized __via__ the reaction of 2,4‐dihydro‐4‐benzyl‐5‐(isomeric pyridyl)‐3H‐1,2,4‐triazole‐3‐thione **1a**, **1b**, **1c** with ethyl chloroacetate, hydrazine hydrate, and acetyl aceton