✦ LIBER ✦

Synthesis of Some New 1,2,4-Triazole Derivatives by Mitsunobu Chemistry

✍ Scribed by Abdolali Alizadeh

Book ID: 102261073
Publisher: John Wiley and Sons
Year: 2005
Tongue: German
Weight: 67 KB
Volume: 88
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.200590218

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The reactive 1 : 1 intermediate produced in the reaction between triphenylphosphine and diisopropyl azodicarboxylate has been trapped by isocyanates or isothiocyanates to yield 1,2,4‐triazole derivatives 2 (Scheme 1). The structures of the highly functionalized compounds 2 were corroborated spectroscopically (IR, ^1^H‐ and ^13^C‐NMR, EI‐MS) and by elemental analyses. A mechanism for this type of cyclization is proposed (Scheme 2).

📜 SIMILAR VOLUMES

Synthesis of Some New 1,2,4-Triazole Der

Synthesis of Some New 1,2,4-Triazole Derivatives by Mitsunobu Chemistry.

✍ Abdolali Alizadeh 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 16 KB 👁 2 views

Synthesis and Antimicrobial Activities o

Synthesis and Antimicrobial Activities of Some New 1,2,4-Triazole Derivatives

✍ Bektaş, Hakan; Karaali, Nesrin; Şahin, Deniz; Demirbaş, Ahmet; Karaoglu, Şengül 📂 Article 📅 2010 🏛 Molecular Diversity Preservation International 🌐 English ⚖ 223 KB

Synthesis and antiviral activity of some

Synthesis and antiviral activity of some new 1H-1,2,4-triazole derivatives

✍ OG Todoulou; AE Papadaki-Valiraki; S Ikeda; E De Clercq 📂 Article 📅 1994 🏛 Elsevier Science 🌐 French ⚖ 945 KB

Mass spectra of some 1,2,4-triazole deri

Mass spectra of some 1,2,4-triazole derivatives

✍ K. T. Potts; R. Armbruster; E. Houghton 📂 Article 📅 1971 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 231 KB

Synthesis of certain 1,2,4-triazole nucl

Synthesis of certain 1,2,4-triazole nucleoside derivatives

✍ Josephine Michael; Steven B. Larson; Morteza M. Vaghefi; Roland K. Robins 📂 Article 📅 1990 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 641 KB

Synthesis and Antibacterial Activity of

Synthesis and Antibacterial Activity of Some New Derivatives of Thiosemicarbazide and 1,2,4-Triazole

✍ Wujec, Monika; Pachuta-Stec, Anna; Stefańska, Joanna; Kuśmierz, Edyta; Siwek, Ag 📂 Article 📅 2013 🏛 Taylor and Francis Group 🌐 English ⚖ 135 KB