Synthesis of some naturally occurring drimane and dinorlabdane derivatives

✍ Scribed by Weyerstahl, Peter ;Schwieger, Ralf ;Schwope, Ina ;Hashem, Md. Abul

• Publisher: John Wiley and Sons
• Year: 1995
• Tongue: English
• Weight: 359 KB
• Volume: 1995
• Category: Article
• ISSN: 0947-3440
• DOI: 10.1002/jlac.1995199507187

✦ Synopsis

Abstract

The naturally occurring (ex Hedychium acuminatum) compounds drim‐8(12)‐ene (1), albicanal (4), (E)‐15,16‐dinorlabda‐8(17), 11‐dien‐13‐one (5), and (E)‐15, 16‐dinorlabda‐8(17), 12‐dien‐14‐al (9), were prepared as racemates by starting from the synthetically available rac‐albicanol (2). – The Nozaki reaction of the trimethyldecalone 10 yields 11‐nordrim‐8‐en‐12‐al (11) and its Δ7 regioisomer 12.