Synthesis of some 2-(heteroarylamino)benzimidazoles and their cyclization with phosgene
✍ Scribed by Ricardo Bossio; Stefano Marcaccini; Valerio Parrini; Roberto Pepino
- Book ID
- 112127957
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1985
- Tongue
- English
- Weight
- 136 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0022-152X
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## Abstract 5,6‐Dichloro‐2‐hydroxymethyl‐1__H__‐benzimidazole (**1**) was prepared by the cyclization of 4,5‐dichloro‐o‐phenylenediamine with glycolic acid, then, alcohol group of **1** was converted to carboxylic acid (**2**). The final products 5,6‐dichloro‐1__H__‐benzimidazole‐2‐carboxamides (**
Synthesis and Reactions of Some New Benzimidazoles. Part 2. -Starting from known, biologically active compounds of type (III) various modifications are carried out to test new types of compounds for their antimicrobial activity. Compounds (VI), (VIIIa), and (XI) show moderate activity against Pseud