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Synthesis of somatostatin analogs resistant to the action of trypsin

✍ Scribed by ALLEN, MARK C. ;WADE, ROY

Book ID
115098770
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
544 KB
Volume
32
Category
Article
ISSN
0367-8377

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Synthesis and physicochemical characteri
Synthesis and physicochemical characterization of the lanthionine analog of somatostatin[1–14]
✍ George Γ–sapay; Giuseppe Melacini; Qin Zhu; Lida Tehrani; Murray Goodman πŸ“‚ Article πŸ“… 1994 πŸ› Springer Netherlands 🌐 English βš– 426 KB

The synthesis of the lanthionine analog of somatostatin[1-14] on a Kaiser-oxime resin is described. The 12residue peptide segment [3][4][5][6][7][8][9][10][11][12][13][14] was assembled and cyclized on the resin by using the method of peptide cyclization on an oxime resin (PCOR); the product was obt