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Synthesis of Secondary Enamides by Ruthenium-Catalyzed Selective Addition of Amides to Terminal Alkynes

✍ Scribed by Lukas J. Gooßen; Kifah S. M. Salih; Mathieu Blanchot

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
361 KB
Volume
120
Category
Article
ISSN
0044-8249

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The enamide group is an important substructure that is often found in natural products [1] and synthetic drugs that have, amongst others, sedative, [2] cytotoxic, [3] or anti-inflammatory [4] properties. Moreover, they are versatile synthetic intermediates that can serve as substrates for polymeriza