𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of (S)-(+)-6-aryl-3-acetyl-6-trifluoromethyl-5,6-dihydropyridin-2(1H)-ones

✍ Scribed by N. M. Golovach; V. A. Sukach; M. V. Vovk

Book ID
111465436
Publisher
SP MAIK Nauka/Interperiodica
Year
2010
Tongue
English
Weight
185 KB
Volume
46
Category
Article
ISSN
1070-4280

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Diastereoselective synthesis of 3,6-disu
Diastereoselective synthesis of 3,6-disubstituted 3,6-dihydropyridin-2-ones
✍ Thomas F. Anderson; Julian G. Knight; Kirill Tchabanenko πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 162 KB

In a short sequence, 5-vinyloxazolidin-2-ones were converted into the 3,6-disubstituted 3,6-dihydropyridin-2-ones via Pd-catalysed carbonylation and enolate alkylation with high diastereoselectivity. Alkylation of 6-substituted N-methylpyridin-2ones gives stereoselectively the 3,6-anti diastereoisom