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Synthesis of (S)-2-Ethoxy-3-phenylpropanoic Acid Derivatives and Their Insulin-Sensitizing Activity.

✍ Scribed by Ying-Hua Wu; Bing Xia

Publisher
John Wiley and Sons
Year
2007
Weight
14 KB
Volume
38
Category
Article
ISSN
0931-7597

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Synthesis of (S)-2-Ethoxy-3-Phenylpropan
Synthesis of (S)-2-Ethoxy-3-Phenylpropanoic Acid Derivatives and Their Insulin-Sensitizing Activity
✍ Ying-Hua Wu πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 50 KB

## Abstract A series of (__S__)‐2‐ethoxy‐3‐phenylpropanoic acid derivatives were synthesized and their insulin‐sensitizing activities were evaluated in 3T3‐L1 cells. Compounds **1b**, **1d**, **1e** and **1f** exhibited more potent insulin‐sensitizing activity than rosiglitazone.