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Synthesis of RGD amphiphilic cyclic peptide as fibrinogen or fibronectin antagonist

✍ Scribed by Mamadou Amadou Sow; Annie Molla; Frédéric Lamaty; René Lazaro

Book ID
110268669
Publisher
Springer Netherlands
Year
1997
Tongue
English
Weight
83 KB
Volume
4
Category
Article
ISSN
1573-3149

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Synthesis of RGD analogues containing α-Tfm-arginine as potential fibrinogen receptor antagonists
✍ Alma Dal Pozzo; Laura Muzi; Maurizio Moroni; Riccardo Rondanin; Roberto de Casti 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 555 KB

AIImraet The ~ of two ~ mimetics of RGD, ct-Tfm-Arg-Gly-Asp-Phe-NHz 9 anti ct-Tfm-Arg431y-Asp-NH-(CH2h-C6Hs 13, is desmb~ The precursor of ct-Tfin-omithine was obtained in two s~ steps from 2-N-C~-2-T[m-hexkncdiaO\_ " \_\_'d\_-l-all~-! ester and introduced into the peptide chain by tz-catboxy-group