✦ LIBER ✦
Synthesis of Reactive Intermediates for Natural Cyclopentane Derivatives from (−)-Quinic Acid: Preparation of 11α-hydroxy-13-oxaprostanoic acid
✍ Scribed by Jean-Claude Barrière; Angèle Chiaroni; Jeanine Cléophax; Stephan D. Géro; Claude Riche; Mare Vuilhorgne
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- German
- Weight
- 242 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
We describe a flexible, stereocontrolled synthesis of enantiomerically pure substituted cyclopentenes and cyclopentanes ‐ including 11α‐hydroxy‐13‐oxaprostanoic acid 20 ‐ (−)‐quinic acid via an acyclic precursor 6 by an intramolecular aldolisation‐dehydration reaction.